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碳酸锂在甲亢治疗中有哪些作用?

来源:华人健康网 | 发布时间:2011-03-08 15:13:35 | www.chinesejk.com
碳酸锂是一种抗狂躁症药,临床上主要用来治疗狂躁性精神分裂症,现以小剂量治疗甲亢。本品能抑制甲状腺素的释放,使血清中甲状腺素水平下降。此外,锂盐还可以作用于骨髓,增加末梢白细胞的数量,当甲亢合并粒细胞减少时,或用硫脲类药物、咪唑类药物使白细胞下降时,合用碳酸锂疗效更佳。锂盐口服吸收快而完全,抗甲亢所需药物浓度较高,易发生中毒,出现头晕、恶心、呕吐、腹痛、腹泻,甚则意识模糊、震颤、反射亢进、癫痫发生等,一旦出现,应立即停药,同时补液,静推氨茶碱,促进锂的排泄。锂剂一般不作为抗甲亢的常用药物,当碘化物过敏,或抗甲状腺药物不宜使用,严重甲亢病人及急需术前准备者,可应用碳酸锂,每日0.9~1.5克,分3次口服。

碳酸锂对伴有严重心肾病患者、电解质紊乱者、妇女孕妊前3个月及哺乳期者忌用。不宜同非甾体抗炎药物同时使用,对老年患者应慎用。

(编辑:小鱼 )

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