·加入收藏 ·设为首页 ·网站地图

2型糖尿病患者有骨骼肌线粒体功能障碍

来源:华人健康网 | 发布时间:2011-04-25 11:01:46 | www.chinesejk.com

  美国匹兹堡大学医学院内科Atzmon等报告,2型糖尿病病人的骨骼肌线粒体生物能生成量减少,肥胖者也存在这种现象。(Diabetes 2002512944)

  该研究共纳入体瘦及肥胖的非糖尿病志愿者(各10名)和10例2型糖尿病病人。在空腹条件下,Atzmon等经皮取受试者股外侧肌活检标本,检测线粒体鱼藤酮敏感性NADH:O2氧化还原酶活性,后者反映呼吸链的总活性。检测肌酸激酶和柠檬酸合酶活性,分别作为肌细胞和线粒体含量的标志物。

  结果显示,2型糖尿病病人NADHO2氧化还原酶活性最低,体瘦志愿者NADHO2氧化还原酶活性最高,肥胖志愿者居中(P<0.005)。同样,2型糖尿病病人柠檬酸合酶活性也有所降低(P<0.005)。电子显微镜检查显示,2型糖尿病病人和肥胖者的骨骼肌线粒体比体瘦志愿者显著缩小(P<0.01)。

(编辑:阳阳 )

  • {get sql="select contentid,catid,url,title from content_content where contentid > '$contentid' and catid='$catid' order by contentid asc" rows="1" return="s"} 上一篇: {/get}
看了本文的网友还看了:(搜索相关文章:Array )
    {tag_内容页相关信息}

[收藏] [打印] [关闭] [返回顶部]

频道精彩推荐

保健
健身
减肥
美容
整形
{get sql="SELECT contentid,title,url,description,thumb FROM `phpcms_content` WHERE contentid IN (SELECT contentid FROM phpcms_content_position WHERE posid=6) AND status=99 $cats120 ORDER BY contentid DESC" rows="1"}

……【查看详细

{/get}
    {get sql="SELECT contentid,title,url FROM `phpcms_content` WHERE contentid NOT IN (SELECT contentid FROM phpcms_content_position WHERE posid=6) AND status=99 $cats120 ORDER BY contentid DESC" rows="4"}
  • {/get}
    {get sql="SELECT contentid,title,url,thumb FROM `phpcms_content` WHERE thumb!='' AND status=99 $cats11 ORDER BY contentid DESC" rows="4"}
  • {/get}
糖尿病文章
    {get sql="SELECT contentid,title,url FROM `phpcms_content` WHERE status=99 $cats1006 ORDER BY contentid DESC" rows="8"}
  • {/get}
胃病文章推荐
    {get sql="SELECT contentid,title,url FROM `phpcms_content` WHERE status=99 $cats1067 ORDER BY contentid DESC" rows="8"}
  • {/get}
    {get sql="SELECT contentid,title,url,thumb FROM `phpcms_content` WHERE contentid IN (SELECT contentid FROM phpcms_content_position WHERE posid=6) AND status=99 $cats382 ORDER BY contentid DESC" rows="2"}
  • {/get}
    {get sql="SELECT contentid,title,url,thumb FROM `phpcms_content` WHERE contentid IN (SELECT contentid FROM phpcms_content_position WHERE posid=6) AND status=99 $cats1325 ORDER BY contentid DESC" rows="2"}
  • {/get}
妇科文章推荐
    {get sql="SELECT contentid,title,url FROM `phpcms_content` WHERE status=99 $cats653 ORDER BY contentid DESC" rows="8"}
  • {/get}
男科文章推荐
    {get sql="SELECT contentid,title,url FROM `phpcms_content` WHERE status=99 $cats654 ORDER BY contentid DESC" rows="8"}
  • {/get}
关于我们| 设为首页 | 加入收藏 | 网站地图 | 友情链接 | 业务联系 | 频道合作
Copyright © 2009 chinesejk.com All Rights Reserved 华人健康网 版权所有
本站如有转载或引用文章涉及版权问题,请速与我们联系 QQ:6875839
特别声明:本站内容仅供参考,不作为诊断及医疗依据。
闽ICP备09040914号