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过氯酸钾在甲亢治疗中有哪些作用?

来源:华人健康网 | 发布时间:2011-11-24 14:05:05 | www.chinesejk.com
过氯酸钾及某些单价阴离子如SCN-、CIO4-或NO3-等能阻止甲状腺摄取和浓集碘化物,从而使甲状腺素的合成不能进行,1954年由Godley作为抗甲状腺药物推荐于临床。硫氰酸钾的药物作用与过氯酸钾相似,但作用较弱,临床上一般只用过氯酸钾。

过氯酸钾每次200~400毫克,日服3次,毒副反应有胃部不适、皮疹、发热、淋巴结肿大和白细胞减少等。另一突出的缺点是,如先于碘剂服用,则碘剂在过氯酸钾的影响下将起不到应有的作用。此药在我国偶尔用作T4抑制试验。

(编辑:小鱼 )

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